First International Workshop on Genetic Epidemiology
of Complex Traits using Twins and Sib-Pairs
Aim:
The workshop focuses on methodological and epidemiological issues
concerning the use of twins and sib-pairs in analysis of complex traits.
When:
March 26-27, 1998
Where:
St.Catharine's College, Cambridge, United Kingdom
Day I: Use of Twins and Sib-pairs in Epidemiological Research
9.00-10.00 Registration and coffee
10.00-10.15 Introduction. Tim Spector (London, UK)
10.15-10.45 Volunteer vs. registry based twin studies. David Strachan (London, UK)
10.45-11.15 Subject selection and case definition. Jaakko Kaprio (Helsinki, Finland)
11.15-11.45 Fetal programming or genes? David Phillips (Southampton, UK)
11.45-12.15 Generalisability of twin studies. Kirsten Kyvik (Denmark)
12.15-12.45 Panel discussion
Lunch
13.45-14.00 Introduction. David Strachan (London)
14.00-14.30 Biases. Alex MacGregor (London, UK)
14.30-15.00 Co-twin case control study. To be confirmed
Break
15.15-15.45 The genetic architecture of intermediate traits.
Charles Sing (Ann Arbor, Michigan, USA)
15.45-16.15 Gene environment interaction. Nick Martin (to be confirmed)
16.15-17.00 Panel discussion
Break
Evening session: Implications and future developments
17.30-17.45 Introduction. To be confirmed
17.45-18.05 Twin & sib-pair studies in developing countries.
Xiping Xu (Harvard, USA)
18.05-18.25 Legal/commercial/ethical implications. Martin Bobrow
(Cambridge, UK)
18.25-18.45 Pharmacogenetics. Roland Wolf (Dundee, UK)
18.45-19.15 Panel discussion
Day 2: From heritability to QTL detection
8.30-8.45 Introduction. Joanne Meyer (Boston, USA)
8.45-9.15 ANOVA analysis of twin data. Joe Christian (Indianapolis, USA)
9.15-9.45 Path analysis of twin data. Harold Snieder (London, UK)
9.45-10.15 Multivariate model fitting. Dorret Boomsma (Amsterdam, Holland)
Break
10.45-11.15 Non-parametric methods. Mathias Chiano (London, UK)
11.15-11.45 Survival analysis methods. Andrew Pickles (London,UK)
11.45-12.30 Panel discussion
Lunch
13.30-13.45 Introduction. David Clayton (Cambridge, UK)
13.45-14.30 Variance component approaches in QTL mapping. David Fulker (London,UK)
14.30-15.15 Use of twins in QTL analysis. Nik Schork (Cleveland, USA)
Break
15.45-16.30 Multipoint sib-pair analysis of quantitative traits. Leonid Kruglyak (Boston, USA)
16.30-17.15 Statistical & software tools for QTL analysis. Mike Neale (Richmond, VA, USA)
17.15-18.00 Panel discussion
FINISH
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Further information on registration (numbers strictly limited):
Early bird/academic discounts before the 1st of November.
Dr Harold Snieder
Twin Research Unit
St. Thomas' Hospital
London SE1 7EH
Email: h.snieder@umds.ac.uk
Web: http://www.umds.ac.uk/twin-unit/