Post doc, Karolinska Institutet
The Department of Medical Epidemiology and Biostatistics invites applications for
Post doc position in biomarkers to predict outcome in psychiatry
Brief description of Project
The ultimate goal of this project (Biomarkers in psychiatry) is to provide tools for clinical use to enable personalized psychiatric care. The task is to investigate in detail and write papers on the relationship between biomarkers (DNA, proteins and peptides in serum and cerebrospinal fluid) and risk for psychiatric disorders, prognosis, and treatment outcome. Applicants will also contribute to new collections of biological samples coupled to psychiatric quality registers. The project is funded through The Swedish Foundation for Strategic Research. The applicant will have access to collected DNA from 10,000 patients with bipolar disorder (The Stanley study) and schizophrenia (The Broad study) linked to data on drug use, side effects, and other variables. The main research questions will concern which biological variables that are associated with diagnosis, specific phenotypes, treatment outcomes, adverse effects (including recurrence and death), but there is also room for new research ideas.
Applicants should have a PhD degree in health sciences, psychiatric genetics, clinical epidemiology, or statistics /biostatistics. The applicant should be skilled in advanced multivariate statistics and have ample experience with publishing English research articles. Interest in psychiatric research is a prerequisite and some basic knowledge of this research field is an advantage.
Appointment will be for 2 years (1+1), with a possible extension after evaluation.
Description of the working group and Department
The Department of Medical Epidemiology and Biostatistics presently employ approximately
250 staff with 15 full professors and over 40 graduate students. The department is one of the biggest departments of epidemiology in Europe. Unique resources and prerequisites – such as the Swedish Twin Registry, several large prospective studies, ongoing nation-wide case-control studies, large nation-wide databases including the Cancer Registry and the Patient Registry, record linkage capabilities and access to clinical data as well as biological material – are effectively explored at the department. Further information can be found at the website
The psychiatric epidemiology group comprises 5 professors/associate professors, 1 guest professor, 2 post docs, and 15 PhD-students. The group is involved in a wide variety of psychiatric research projects, including population-based cohort and case-control studies, twin and family studies, survival analyses, predictive modeling, genetic epidemiology and bioinformatics.
For further information regarding this positions, please contact Guest professor Mikael Landén, e-mail Mikael.email@example.com Professor Christina Hultman, e-mail firstname.lastname@example.org or Professor Paul Lichtenstein, e-mail email@example.com
Ulrika Zagai (SACO), e-mail firstname.lastname@example.org Tel: 08-524 871 84
Ann Almqvist (OFR/ST-AT), e-mail email@example.com Tel: 08-524 861 99
Gunnar Stenberg (SEKO), e-mail firstname.lastname@example.org Tel: 08-524 880 75
Please send your application, marked with reference number 7376/2011, to mailto:email@example.com or Karolinska Institutet, Åsa Misic, Box 281, 171 77 Stockholm, Sweden. Applicants should send letter of application, the names and contact information of three references, a CV and brief statement of research goals which should reach us by no later than 15 December 2011.